Screening for anal cancer and precancer with a new HPV test
Part of Cancer, Digestive system, Infections clinical trials.
This study tests how well a special HPV test (called BD Onclarity™) can find anal cancer or precancer. It is for people at high risk or with known anal abnormalities, and aims to improve early detection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You either have been diagnosed with anal precancer (AIN1 or AIN2+) or anal cancer confirmed by biopsy, OR you are in one of these high-risk groups: weakened immune system (due to HIV, immunosuppressive drugs, or organ transplant), a man who has sex with men, a woman over 40 with a history of cervical precancer (CIN2+) or vulvar cancer, or have Crohn's disease affecting the anal area.
- You may also qualify if you are undergoing routine colorectal cancer screening.
- You must be willing to sign a consent form to take part.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial checks whether tumor samples contain HPV DNA (genetic material from the HPV virus). The goal is to improve detection in anal and cervical cancers, especially in patients planning standard radiation treatment.
This study is screening gay and bisexual men for anal cancer by taking a swab sample. It aims to find early signs of cancer so it can be treated early.
This study is testing a new way to screen for anal cancer by looking at DNA methylation in cells collected from the anus. It may help people at higher risk for anal cancer find out earlier if they need further tests.
This study tests whether having people collect their own anal samples at home can help find and treat early signs of anal cancer. It is for men and transgender women who have sex with men and who live in or near Chicago, Houston, or Milwaukee.
This trial checks whether anal cancer screening is useful for women age 40 and older who previously had high-grade vulvar pre-cancer (VIN 2/3) or vulvar cancer. It may help find serious problems earlier in people at higher risk.
This study tests a self-collected anal swab for detecting HPV (the virus that can cause anal cancer) in people living with HIV. It aims to see if this simple swab is as accurate as a doctor-collected sample, and may help prevent anal cancer.
Hear when a new Anal Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.