THC and d-limonene for cannabis anxiety
This study tests if a natural compound called d-limonene (found in citrus oils) can reduce anxiety that some people feel after using high-THC cannabis. You'll receive THC and d-limonene in capsules under medical supervision.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 21 to 55
- Good general health (checked by study doctor)
- Negative drug test (except cannabis) and no heavy other drug use
- Not pregnant or nursing, and use birth control if female
- Have used high-THC cannabis in the past 3 years and felt anxious from it at least once
- No prescription or OTC meds (except birth control) for 14 days before sessions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests different ratios of CBD to THC to see how CBD can change the effects of THC. It may help people who use cannabis occasionally understand how CBD can reduce unwanted side effects.
This study looks at how high-potency cannabis concentrates affect people who already use cannabis a few times a week. You will be asked to vape a concentrate and then have your reactions monitored.
This Phase 1 study tests how inhaled THC and a natural plant chemical called myrcene affect behavior, thinking, and safety in healthy adults. You may help researchers understand potential brain/behavior effects before larger studies.
This study tests whether a cannabis-like drug can help people with higher-than-normal anxiety cope with a night of very little sleep. You will be asked to sleep only 4 hours on one occasion.
This study tests an inhaled medication called NC-107 to see if it can safely reduce anxiety symptoms compared to a placebo over 4 weeks. It is for adults with generalized anxiety disorder who have not used cannabis regularly.
This study looks at whether different types of cannabis (containing THC and/or CBD) might help people who use cannabis regularly reduce potential harms. You will be asked to take cannabis in a controlled setting and complete tasks and questionnaires.
Hear when a new THC trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.