Clin2
NCT06386003Possibly a fitRecruiting

Psilocybin and talk therapy for chronic PTSD

Post Traumatic Stress DisorderPTSDChronic PTSD

Treatments studied

Part of Mental health clinical trials.

This trial tests whether a medication called psilocybin (the active ingredient in magic mushrooms) can help people with long-term PTSD when combined with a specific type of talk therapy. The goal is to see if this approach reduces PTSD symptoms more than therapy alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
15 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You have been diagnosed with PTSD and have had symptoms for at least 6 months.
  • Your PTSD symptoms are moderate to severe (as measured by a standard checklist).
  • You are willing to stop taking any psychiatric medications during the study period.
  • You are not pregnant or nursing, and you agree to use effective birth control if you can become pregnant.
  • You do not have a history of certain mental health conditions like schizophrenia, bipolar disorder, or borderline personality disorder.
  • You do not have serious heart problems, high blood pressure, liver disease, or a history of seizures.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07506395Recruiting· Phase 1
Psilocybin group therapy for PTSD

This study tests if psilocybin-assisted group therapy can help people with moderate to severe PTSD. It is for veterans, first responders, female survivors of sexual violence, or Indigenous individuals.

Albuquerque, New Mexico
NCT06888128Recruiting· Phase 2
Psilocybin for PTSD in veterans

This study tests whether a guided psilocybin session can help veterans heal from trauma-related PTSD. If you're a veteran with PTSD, you may be able to join.

Houston, Texas
NCT07104916Recruiting· Phase 2
Mindfulness and psilocybin therapy for PTSD

This study tests whether a combination of mindfulness training and a single dose of psilocybin can help reduce PTSD symptoms. It is for people with moderate-to-severe PTSD who are not on certain medications and do not have major health problems.

Columbus, Ohio
NCT07745569Not yet recruiting· Phase 2
Psychedelic therapy study for depression or PTSD

This study tests whether electromagnetic brain stimulation and a psychedelic drug called psilocybin can help people with depression or PTSD. It aims to see how these treatments affect mood and behavior, and whether they are safe and helpful.

NCT06902974Recruiting· Phase 2
Psilocybin therapy for PTSD from sexual assault

This trial tests whether psilocybin, a psychedelic drug given in a supportive therapy setting, can help women heal from post-traumatic stress disorder (PTSD) caused by a sexual assault that happened 6 or more months ago. You'll receive the drug during supervised sessions and attend therapy visits to see if it reduces your PTSD symptoms.

Rockville, Maryland
NCT07332143Not yet recruiting· Phase 2
Psilocybin therapy for PTSD in Georgia veterans

This trial tests whether a drug called psilocybin, combined with therapy, can help treat PTSD. It is for Georgia military members and veterans who have had PTSD for at least 6 months.

Atlanta, Georgia

Hear when a new PTSD trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.