Antibiotic to prevent UTI after bladder Botox
Treatments studied
Part of Infections, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and being treated at the Walter Reed Urogynecology clinic.
- You have been diagnosed with overactive bladder (OAB) or interstitial cystitis/bladder pain syndrome (IC/BPS).
- You are planning to receive Botox injections into your bladder for your condition.
- You do not currently have a urinary tract infection (UTI) or a history of frequent UTIs.
- You are not allergic to the antibiotic nitrofurantoin, and your kidneys work well enough (creatinine clearance above 30).
- You are not taking any antibiotics right now, and you don't have a condition that affects bladder nerves (neurogenic bladder).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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