Clin2
NCT06485505Possibly a fitRecruiting

Isotretinoin vs light for nail fungus treatment

Onychomycosis

Treatments studied

Part of Infections, Skin clinical trials.

This trial compares two treatments for nail fungus (onychomycosis): a medication called isotretinoin and a special light therapy (excimer light) used alongside standard care. It aims to find which works better as an add-on treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
36 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You have a fungal infection in one or more nails.
  • You are not pregnant or breastfeeding.
  • You are not currently taking statins (cholesterol medication) or any drugs that make your skin sensitive to light.
  • You do not have liver disease, heart disease, or diabetes.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07033962Not yet recruiting
Laser, urea or fluconazole for fungal nail infection

This study compares a fractional CO₂ laser, 40% urea, or a fluconazole microemulsion applied to the nail to see which works best for treating fungal nail infections (onychomycosis). It may help you if you have a confirmed fungal nail infection and haven't used certain antifungal treatments recently.

NCT06689852Recruiting
Study of two treatments for nail fungus

This trial tests two different treatments for fungus that affects the fingernails or toenails. It is designed to see how well the treatments work and if they are safe.

Villeurbanne, France
NCT06327295Recruiting· Phase 2
Testing a new treatment for mild to moderate toenail fungus

This trial tests an investigational medication called ATB1651 for people with toenail fungus (onychomycosis). If you have a fungal infection covering 20% to 60% of one or both big toenails and are in generally good health, you may be able to join.

Christchurch
NCT07675239Not yet recruiting· Phase 4
Comparing two treatments for ringworm on the body

This trial tests if adding a second medication, isotretinoin, to the standard itraconazole treatment works faster or better for adults with ringworm on their body. It aims to find a safer and more effective way to treat this common fungal skin infection.

Rawalpindi, Punjab Province
NCT06447480Recruiting· Phase 3
Comparing isotretinoin to standard care for moderate acne in darker skin

This trial compares oral isotretinoin (a strong acne medication) to standard treatments for people with moderate acne and darker skin tones. It aims to find which treatment works best for skin of color.

Nice, Alpes-Maritimes
NCT07756671Not yet recruiting· Phase 1
Light therapy for fungal nail infection

This study tests a light-based treatment (photodynamic therapy) for fungal nail infections. It may help clear the infection without oral medication.

Arlington, Texas

Hear when a new Onychomycosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.