Sintilimab with chemo and growth factor before esophageal cancer surgery
Part of Cancer, Digestive system clinical trials.
This trial tests whether giving the immunotherapy drug sintilimab together with standard chemotherapy and a growth factor injection before surgery can help people with a certain type of esophageal cancer (squamous cell carcinoma) that is still removable. The goal is to improve treatment outcomes before the operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to 75 years old.
- You must have a type of esophageal cancer called squamous cell carcinoma that has not spread to the neck, is in the middle or lower part of the esophagus, and can likely be removed with surgery.
- You cannot have received any previous cancer treatment, such as chemotherapy, radiation, or surgery.
- You must be in fairly good health, able to do daily activities with little to no help, and have adequate blood counts, liver, and kidney function.
- You must be willing to provide tissue and blood samples for research and, if you are able to become pregnant, use effective birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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