Study of treatments before surgery for esophageal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial is testing different treatment combinations before surgery for people with locally advanced esophageal squamous cell carcinoma. The goal is to find which approach works best based on specific biomarkers like PD-L1 levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with esophageal squamous cell carcinoma (a type of cancer in the esophagus).
- Your cancer is locally advanced (has spread nearby but not to distant organs) and your doctor says it can be removed with surgery.
- You are between 18 and 75 years old.
- You are generally active and able to take care of yourself (ECOG score 0 or 1).
- A test result for PD-L1 (a marker on cancer cells) is available.
- Your blood counts, liver function, and kidney function are within acceptable ranges.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies investigational cancer medicines, either alone or along with pembrolizumab, for people with advanced esophageal squamous cell cancer whose cancer has grown despite prior immune and platinum-based treatment. It may offer a new option after standard therapy has not worked.
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