Predicting success and side effects of endoscopic ampullectomy
Part of Cancer clinical trials.
This study looks back at people who had a non-cancerous growth (adenoma) removed from the ampulla—the opening where the bile and pancreatic ducts meet the intestine—using an endoscope (a thin tube with a camera). Researchers want to learn what makes the procedure more likely to succeed and what side effects people may have, so they can better guide future patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and have had an endoscopic ampullectomy (a scope-based procedure to remove a growth at the opening of your bile duct).
- The removed growth was an adenoma (a non-cancerous polyp) with low-grade or high-grade dysplasia (abnormal cells that are not cancer) on biopsy before the procedure.
- The growth was 30 mm (about 1.2 inches) or smaller, including if it spread sideways.
- The growth did not extend into the bile or pancreatic ducts, and there were no signs of invasive cancer (like a hard texture, ulceration, or bleeding).
- You have been followed for at least one year after the procedure.
- You have not had a prior endoscopic or surgical removal of the same area, and you do not have pancreas divisum (a birth variation in the pancreas).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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