Esophageal replacement with a decellularized human esophagus graft
Part of Digestive system clinical trials.
This study tests a new way to replace a narrowed esophagus (the tube that carries food to the stomach) using a specially treated donor esophagus. It is for people whose esophageal narrowing (stricture) has not improved with standard dilation treatments. The goal is to see if this graft can safely and effectively improve swallowing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have a benign (non-cancerous) narrowing of the esophagus that did not get better with dilation (stretching) treatment.
- The narrowing may be due to swallowing chemicals, injury, surgery, radiation, or certain endoscopic procedures.
- If you are a woman who could become pregnant, you must use effective birth control during the study and have a negative pregnancy test before starting.
- You must be able to attend follow-up visits and sign a consent form.
- You must not have significant weight loss, a very long narrowing (>5 cm), or multiple narrowings.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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