Clin2
NCT06689514Possibly a fitRecruiting

Tranilast for enlarged prostate (medium to large volume)

Prostatic Hypertrophy, Benign

Part of Kidney & urinary clinical trials.

This trial tests a drug called Tranilast to see if it can improve urinary symptoms caused by an enlarged prostate. It focuses on men with moderate to severe symptoms and a prostate size greater than 40 mL.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
30 people
Ages
55 years to 75 years
Study type
Interventional

Who can take part

  • You are between 55 and 75 years old.
  • Your prostate is larger than 40 mL (about the size of a golf ball or bigger).
  • You have urinary symptoms like trouble starting or weak stream, with a symptom score of 8 or higher, or a maximum flow rate less than 15 mL per second.
  • You do not have other causes of urinary blockage, like a urethral stricture.
  • You do not have major organ problems like liver or kidney issues, and you are not taking the blood thinner warfarin.
  • You are not allergic to Tranilast or similar drugs, and you have no history of bladder or prostate cancer.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07873125Not yet recruiting
Ultrasound-guided prostate lift for enlarged prostate symptoms

This study tests a newer ultrasound-guided method for a prostate lift procedure, which may improve urine flow and reduce symptoms in men with an enlarged prostate. It is an exploratory trial, meaning researchers are checking how well the new approach works compared to the usual method.

Shanghai
NCT07870759Not yet recruiting· Phase 3
Combination therapy for enlarged prostate symptoms

This trial tests whether combining two medicines works better than one alone for easing urinary symptoms caused by an enlarged prostate. If you have bothersome symptoms and a larger prostate, this study may help you find a more effective treatment.

NCT05401032Recruiting· Phase 2
Tryptophan for urinary symptoms from prostate enlargement

This Phase 2 study tests whether tryptophan is safe and can improve urinary symptoms caused by an enlarged prostate (BPH). It focuses on men who have bothersome, stable symptoms and who would normally take tamsulosin.

Braga
NCT06062875Recruiting· Phase 2
Testing a drug for enlarged prostate symptoms

This trial tests whether a drug called adalimumab (a TNF blocker) can improve symptoms of an enlarged prostate. It is for men aged 45-80 with a large prostate and bothersome urinary symptoms who have not used this type of medication before.

Glenview, Illinois
NCT07722884Recruiting
Tamsulosin alone or with tadalafil for enlarged prostate symptoms

This study tests whether taking tadalafil (at 2.5 mg or 5 mg) along with tamsulosin is better for treating urinary symptoms caused by an enlarged prostate than taking tamsulosin alone. It aims to find the best dose combination to improve your quality of life.

Cairo, Cairo Governorate
NCT07745621Not yet recruiting
Study of a new device for enlarged prostate symptoms

This trial tests a new device designed to treat symptoms of an enlarged prostate (BPH), such as frequent or difficult urination. It may help improve urine flow and reduce discomfort without traditional surgery.

Panama City, Provincia de Panamá

Hear when a new Prostatic Hypertrophy, Benign trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.