Testing tamsulosin for children with posterior urethral valve
Treatments studied
Part of Kidney & urinary clinical trials.
This trial tests if tamsulosin, a medicine that relaxes muscles in the bladder and prostate, can help children with a condition called posterior urethral valve. It aims to improve how the bladder works and reduce urinary problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child has been diagnosed with posterior urethral valve (a birth defect affecting the urethra).
- Your child does not have other conditions that affect the urinary tract, like spinal problems or certain birth defects.
- Your child has not had a surgery to divert urine flow (like a vesicostomy).
- Your child has not already had the valve treated with surgery at another hospital.
- Your child has no known allergies or problems with alpha-blocker medicines.
- You are willing to have your child participate in the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how children with posterior urethral valves (a condition that affects urination) feel about their quality of life as they grow up. It will help doctors understand how these children are doing emotionally and socially, so they can improve care.
This study looks at how boys who had a procedure to treat a bladder blockage called posterior urethral valve are doing at least one year later. The goal is to understand long-term results and help families know what to expect.
This trial tests whether adding tadalafil to tamsulosin helps men pass a catheter removal test after a first-time urinary blockage caused by an enlarged prostate. The goal is to find which treatment works best to avoid needing a catheter again.
This study tests whether taking tadalafil (at 2.5 mg or 5 mg) along with tamsulosin is better for treating urinary symptoms caused by an enlarged prostate than taking tamsulosin alone. It aims to find the best dose combination to improve your quality of life.
This study compares two medicines (silodosin and tamsulosin) that help with urine flow in men with an enlarged prostate. You would take one medicine for a period, then the other, to see which works better for you.
This trial tests whether early use of oxybutynin can improve bladder and urine behavior in very young boys with posterior urethral valves. It is mainly for babies whose bladder tests show problems even after valve surgery.
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