Lactulose and linaclotide for colonoscopy prep
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether taking lactulose together with linaclotide can improve bowel cleansing before a colonoscopy. If you are scheduled for a colonoscopy, this study may help make the preparation more effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You are able to follow the study schedule and describe your symptoms clearly.
- You are not pregnant, not breastfeeding, and have no plans to become pregnant during the study.
- You have not taken part in any other clinical trial in the past 3 months and will not during this trial.
- You do not have conditions that make colonoscopy unsafe, such as a blocked or torn intestine or severe heart, kidney, or liver problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests if a medication called linaclotide (a pill that helps with constipation) can improve the bowel-cleaning process before a colonoscopy. It may make the preparation easier and more effective.
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This trial compares two ways to clean the bowel before a colonoscopy: a 4-liter split-dose of a laxative plus two other medications versus a 2-liter split-dose with a gas-relief medication. The goal is to see which works better and is easier to tolerate.
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