Digestive enzymes for IBS after diet response
Part of Digestive system clinical trials.
This trial tests whether a digestive enzyme supplement can help people with irritable bowel syndrome (IBS) whose symptoms returned after they previously improved on a special low-FODMAP Mediterranean diet.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have IBS (diarrhea type, mixed type, or unspecified type) as diagnosed by Rome IV criteria.
- You must have taken part in a previous diet study (NCT03997708) and were assigned to the Mediterranean low-FODMAP diet group.
- You either had a good response to that diet but symptoms returned (IBS severity score over 175) a year later, or you couldn't stick with the diet.
- You are willing to take a digestive enzyme supplement and follow the study schedule.
- You are not eligible if you were in the other group (NICE) of the previous study or if your IBS symptoms are currently mild (score under 175).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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