Digestive enzymes for IBS after diet response
Part of Digestive system clinical trials.
This trial tests whether a digestive enzyme supplement can help people with irritable bowel syndrome (IBS) whose symptoms returned after they previously improved on a special low-FODMAP Mediterranean diet.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have IBS (diarrhea type, mixed type, or unspecified type) as diagnosed by Rome IV criteria.
- You must have taken part in a previous diet study (NCT03997708) and were assigned to the Mediterranean low-FODMAP diet group.
- You either had a good response to that diet but symptoms returned (IBS severity score over 175) a year later, or you couldn't stick with the diet.
- You are willing to take a digestive enzyme supplement and follow the study schedule.
- You are not eligible if you were in the other group (NICE) of the previous study or if your IBS symptoms are currently mild (score under 175).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing if a dietary supplement can reduce symptoms of irritable bowel syndrome (IBS). You might qualify if you have been diagnosed with IBS, have moderate to severe symptoms, and are between 18 and 75 years old.
This trial tests whether a low-FODMAP diet can improve gut barrier function in people with irritable bowel syndrome. If you have IBS and are willing to follow a specific diet for a few weeks, this study may help you manage your symptoms.
This trial tests a combination of digestive enzymes and probiotics (called Enzymax DuoBiotics) to see if it can help people with irritable bowel syndrome (IBS) feel better. If you have IBS and are between 18 and 70, this study may be a good fit.
This trial tests whether eating a low-FODMAP diet can reduce IBS symptoms in people who do not have lactose intolerance. It aims to improve moderate-to-severe IBS symptoms by changing what kinds of carbohydrates you eat.
This study tests whether a specific diet plan can improve symptoms in people with IBS that is not constipation (IBS-D or IBS-M). If you qualify, you’ll complete symptom questionnaires and follow the study diet for the trial period to see if symptoms improve.
This study looks for signs in your body—like breath and blood tests—that can show how well you are following a special diet for IBS. It aims to find better ways to track diet compliance, which could help make dietary treatments more effective.
Hear when a new Irritable Bowel Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.