Citrus supplements to prevent nerve pain from paclitaxel
Part of Cancer, Skin clinical trials.
This trial tests whether taking two natural citrus compounds (hesperidin and diosmin) as daily pills can help prevent or reduce nerve damage (tingling, numbness, or pain in hands/feet) caused by the chemotherapy drug paclitaxel. If it works, it could make treatment more comfortable and improve your quality of life during breast cancer therapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older with a confirmed breast cancer diagnosis.
- Your treatment plan includes paclitaxel chemotherapy.
- You need to be in fairly good physical condition (able to care for yourself, but not necessarily fully active).
- You must not already have any numbness, tingling, or pain from nerve damage.
- You cannot have diabetes, heavy alcohol use, heart failure, or be pregnant or breastfeeding.
- You must not have had chemotherapy before.
- You must not have liver or kidney problems or any allergy to hesperidin or diosmin.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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