First-in-human study of AVR-48 in healthy volunteers
This early-stage study tests an investigational drug called AVR-48 in healthy volunteers. You will receive either a single dose or multiple doses to see how the drug is absorbed, processed, and tolerated by your body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a healthy adult between 18 and 55 years old.
- You have not smoked or used nicotine products (including e-cigarettes) for at least 3 months.
- Your body weight is between 110 and 220 pounds (50–100 kg) and your BMI is between 18 and 32.
- You must be generally healthy, with no major medical or mental health conditions, and no history of drug or alcohol abuse in the past 2 years.
- You cannot take any medications, supplements, or herbal products for 2 weeks before and during the study (except acetaminophen up to 2g/day and hormone therapy).
- If you could become pregnant, you must use effective birth control during the study and for 30 days after the last dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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