Liver health check for people taking methotrexate
Part of Digestive system clinical trials.
This study uses a special ultrasound (like a painless scan) and a blood test to check for liver damage in people taking methotrexate. The goal is to find early signs of liver scarring so it can be managed sooner.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You take methotrexate for an autoimmune or skin condition (like rheumatoid arthritis, lupus, psoriasis, or Behçet's disease).
- You do not have a history of liver disease (such as hepatitis B or C, fatty liver disease, cirrhosis, or autoimmune liver disease).
- You have not been diagnosed with heart failure or kidney failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares liver health (including liver ultrasound and blood test results) in people with psoriatic arthritis who have been treated with different biologic medicines or methotrexate for at least 2 years. The goal is to see if one treatment may be more protective for the liver than others.
This trial uses MR elastography (a special MRI) to measure liver stiffness and check for fibrosis (scarring) without a needle biopsy. It may help guide treatment for chronic hepatitis B.
This study looks at how well methotrexate injections work in people with rheumatoid arthritis. It is designed for patients who are starting or changing to this type of methotrexate treatment.
This study is looking for new ways to detect liver scarring (fibrosis) in people with fatty liver disease (NAFLD, NASH, MASLD, or MASH). If you qualify, you will give a blood sample to help identify biomarkers that could replace biopsies.
This study tests a new blood test to help diagnose fatty liver disease and liver fibrosis. It aims to see how well the test works compared with a liver biopsy. Your participation could help improve diagnosis for others.
This study tests a methotrexate injection (given under the skin) for people with moderate to severe rheumatoid arthritis who haven't taken methotrexate before. Researchers want to see how the medicine builds up in your body and if it helps control your symptoms.
Hear when a new Liver Fibrosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.