Laser plus topical methotrexate for vitiligo
Part of Skin clinical trials.
This study tests a new way to treat vitiligo by combining a topical cream (methotrexate) with a special laser treatment (fractional CO2 laser) on similar patches on both sides of the body. It aims to see if this combination helps repigment the skin better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have non-segmental vitiligo (patches on both sides of your body) that has been stable recently.
- You have not used strong steroid creams or light therapy in the last 3 months.
- You are not pregnant and have no other major skin diseases or serious organ problems.
- You are willing to give informed consent to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a combination of narrowband UVB light therapy and steroid cream to see how it affects the immune system in people with vitiligo. It may help reduce the white patches by calming the immune response.
This study compares two ways of applying a medicine called methotrexate to vitiligo patches: one uses a special gel, and the other uses a mild electric current to help the medicine go deeper into the skin. The goal is to see which method helps restore skin color better.
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