Probiotics to prevent diarrhea from neratinib in breast cancer
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests whether taking probiotics can help prevent diarrhea caused by the breast cancer drug neratinib. If you are a woman with HER2-positive breast cancer and are about to start neratinib, this study may help manage a common side effect.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older with HER2-positive breast cancer.
- You are scheduled to receive neratinib treatment (alone or with other drugs).
- You have a good performance status (ECOG 0-2) and expected survival of at least 3 months.
- Your heart function (LVEF) is 50% or higher, and your liver and kidney blood tests are within acceptable limits.
- You do not have any ongoing gut problems like chronic constipation, bloody stools, or stomach pain, and no structural gut issues seen on exams.
- You are not pregnant or breastfeeding and are willing to use effective birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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