TAR-210 vs. standard bladder chemo for high-risk bladder cancer
Treatments studied
Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial compares a new drug called TAR-210, given directly into the bladder, to standard chemotherapy for people with a specific type of high-risk bladder cancer that has not invaded muscle. It tests if TAR-210 can be more effective with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have high-grade bladder cancer that is on the surface (not into muscle), without a type called CIS
- Your tumor has a certain change in the FGFR gene, found by urine or tissue tests
- All visible tumor has been removed before starting the study, and a urine test shows no cancer cells
- You have received BCG treatment in the past, either and it didn't work, or you had side effects from it
- You cannot have or don't want to have bladder removal surgery
- You have a good to moderate ability to perform daily activities (ECOG score 0, 1, or 2)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial compares a new drug, TAR-210, which is placed directly into the bladder, against standard chemotherapy given through a catheter. It is for people with a specific type of bladder cancer that has a change in the FGFR gene.
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