How calcium affects a drug that helps the uterus contract
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This trial tests if adding calcium changes how well a drug called carbetocin works to make the uterus contract after a planned C-section. It may help doctors prevent heavy bleeding after delivery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are not in labor and your pregnancy is between 37 and 41 weeks.
- You are scheduled for your first or second planned C-section.
- You have not received a drug called oxytocin during this pregnancy.
- You are not taking medicines like nifedipine, labetalol, or magnesium sulfate.
- You do not have conditions that raise your risk for heavy bleeding after birth, such as twins, large fibroids, or severe preeclampsia.
- You have not had more than one previous C-section.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if giving carbetocin with calcium helps the uterus contract better after a planned c-section. It's for women at 37+ weeks without high risk for poor uterine tone.
This study compares two medicines—carbetocin and oxytocin—given during a planned cesarean to help prevent heavy bleeding after delivery. It is for women who have certain risk factors for uterine atony (when the uterus does not tighten up after birth).
This study looks at how well different doses of a contraction medicine work after an initial dose in women having a planned C-section. It may help find the best way to prevent bleeding after birth.
This trial studies how a medication called carbetocin affects the heart during a planned cesarean section. Carbetocin helps the uterus contract after delivery to reduce bleeding, and researchers want to see if it changes heart function in healthy women.
This trial studies how three medications (ephedrine, phenylepinephrine, and norepinephrine) affect the contraction strength of uterine muscle tissue from pregnant people with type 2 or gestational diabetes during planned C-sections. It aims to understand if these drugs act differently in people with diabetes, which could help tailor safer treatments for low blood pressure during surgery.
This trial tests if giving calcium through an IV before a C-section can help reduce blood loss in women at higher risk for heavy bleeding due to the uterus not contracting well.
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