UVB and steroids for vitiligo: a biomarker study
Part of Skin clinical trials.
This trial tests whether combining narrowband UVB light with topical steroids can help treat vitiligo, and looks at specific blood markers (CXCL11 and TEMRA) to see how the treatment affects the immune system. It may help patients with stable, non-segmental vitiligo who have not used systemic therapy in the last 3 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have non-segmental vitiligo that has been stable (no new patches or growth) for at least 3 months.
- Your skin type is Fitzpatrick III to V (common in people with olive to brown skin, like many in Egypt).
- You haven't taken any systemic medications (pills or injections) for vitiligo in the past 3 months.
- You do not have a condition that makes you sensitive to light (like lupus or porphyria).
- You are not pregnant or breastfeeding, and do not have an active infection, cancer, or a weakened immune system.
- You have no history of raised scars (hypertrophic scars) or melanoma (a type of skin cancer).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether taking small doses of steroids by mouth for a few days before and after a skin cell transplant (NCES) can reduce the white halo that sometimes forms around the treated area. It is for people with stable vitiligo on the face or trunk that hasn't responded to creams or light therapy.
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This trial compares two types of needle treatments (needling and microneedling) combined with light therapy to see which works better for people with vitiligo that has lasted more than a year.
This study tests whether adding a pill called apremilast to narrowband UVB light therapy works better than light therapy alone for vitiligo. It may help repigment the skin more effectively.
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