Comparing two treatments for Crohn's disease flare-ups
Treatments studied
Part of Digestive system clinical trials.
This trial compares a steroid called prednisolone to a special diet (aCDED with PEN) for treating Crohn's disease flare-ups. It aims to see which approach helps improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have Crohn's disease that affects your small bowel or the right side of your large bowel, confirmed by a colonoscopy.
- Your Crohn's disease is currently active enough to cause symptoms (CDAI score of 150 or higher).
- You haven't taken any steroids in the last 4 weeks.
- You haven't started a new immune-modifying drug in the last 8 weeks.
- You are not currently on any biologic or small-molecule treatments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a special diet (CDED) combined with anti-TNF medication (infliximab or adalimumab) to see if it's safe and works better for active Crohn's disease. It may help if you haven't used these drugs before and can follow the diet.
This study tests whether combining a specific diet with biologic medicines can reduce active inflammation and symptoms of Crohn’s disease. It may help people who still have active disease in the bowel despite prior care.
This trial tests whether a special diet (called an exclusion diet) plus a nutritional supplement can change your gut bacteria and help control active Crohn's disease. It may be a good option if you have mild-to-moderate symptoms and want to try a food-based approach before stronger medications.
This study looks at how a specific amino-acid (threonine) diet affects adults with Crohn’s disease and signs of intestinal inflammation. It may help researchers understand what dietary protein needs could support more stable disease.
This study tests whether a specific diet after Crohn’s surgery can help you recover and stay well. It compares outcomes in people who can follow an exact diet plan after bowel resection.
This study tests whether changing your diet and lifestyle can help repair the lining of your gut if you have Crohn's disease. It focuses on people whose Crohn's causes food-related symptoms or IBS-like symptoms, and involves a special scope procedure to check for food-triggered gut barrier damage.
Hear when a new Nutrition Assessment trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.