IBI343 plus sintilimab and chemo for gastric cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a new combination of IBI343, sintilimab, and chemotherapy for people with advanced stomach or gastroesophageal junction cancer that hasn't been treated yet. It's for those whose tumors are CLDN18.2-positive and not HER2-positive.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced stomach or gastroesophageal junction cancer that can't be removed with surgery or has spread.
- You haven't received any systemic therapy (chemotherapy or other cancer drugs that travel through your bloodstream) for this cancer.
- Your tumor tests positive for CLDN18.2, a specific protein marker.
- You are between 18 and 75 years old.
- Your daily activities are not significantly limited (ECOG performance status 0 or 1).
- Your tumor is not HER2-positive (a different protein marker that would require other treatments).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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