Intravenous lidocaine for pain relief after major abdominal surgery
Part of Digestive system clinical trials.
This study tests whether giving lidocaine through an IV during major open abdominal surgery can improve pain control when combined with spinal morphine. It compares lidocaine to a placebo (a saltwater solution) to see if it reduces pain and improves recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for a major open abdominal surgery (not laparoscopic/minimally invasive).
- You have agreed to receive morphine through a spinal injection for anesthesia.
- You are not having emergency surgery.
- You do not have serious heart problems, severe kidney disease, or liver failure.
- You are not allergic to morphine or lidocaine.
- You are not taking certain medications like pregabalin, gabapentin, or strong daily painkillers.
- You are not pregnant or breastfeeding, and if you could become pregnant, you use effective birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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