FAPI PET-guided radiation with immunotherapy for advanced colorectal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a new combination approach for colorectal cancer that has spread to the abdomen lining. You may receive standard second-line chemotherapy plus an immunotherapy drug (cadonilimab), with or without targeted radiation guided by a special PET scan. The goal is to see if adding radiation and immunotherapy works better than standard therapy alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have colorectal cancer that has spread to the lining of your abdomen and has gotten worse after your first treatment (but you have not had immunotherapy).
- You are in reasonably good health, able to care for yourself, and expected to live at least 6 months.
- Your blood counts, liver and kidney function are within a specific safe range (confirmed by blood tests).
- You are not currently pregnant, and if you could become pregnant, you agree to use effective birth control during the study and for 6 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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