Anti‑inflammatory gel after root canal for pain and swelling
Treatments studied
Part of Pain clinical trials.
This trial tests whether adding a common anti‑inflammatory gel (diclofenac) to the tooth after a root canal can reduce pain and swelling. They will also see if adding another ingredient (hyaluronidase) makes it work even better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and in good general health (no chronic conditions like diabetes or autoimmune diseases).
- You have a tooth with a single root that needs a root canal and has a small infection (5–10 mm) visible on an X-ray.
- You are not allergic to diclofenac or hyaluronidase.
- If you are female, you are not pregnant.
- Your tooth hasn’t had a root canal before, and it isn't cracked or has deep gum pockets.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares pain levels and a protein linked to inflammation (MMP‑9) when a root canal on an infected, dead tooth is done in one visit versus two visits. The goal is to see which approach may be more comfortable for you.
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
This trial compares two types of medicine placed inside the tooth after cleaning to see which one reduces pain better. It is for adults with a dead nerve in a lower premolar tooth who are otherwise healthy.
This trial compares different medicines placed inside the tooth after a failed root canal to help heal the infection at the root tip. If you have a back tooth that still has an infection even though it had a root canal years ago, this study may test which medicine works best for you.
This trial tests whether two new dental rinses, used with special activation methods, can reduce pain and complications after treating teeth with severe pulpitis (tooth nerve inflammation). It may help people with multiple-root teeth who need root canal treatment.
This trial compares two different filling materials used after root canal treatment on dead teeth. Researchers want to see which material causes less pain and swelling afterward.
Hear when a new Periapical Lesion trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.