Pentoxifylline to protect the heart during breast cancer chemo
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests if a medicine called pentoxifylline can help prevent heart damage caused by doxorubicin, a common chemotherapy drug for breast cancer. If you are starting doxorubicin for the first time, this study may offer added heart protection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old.
- You have stage I–III breast cancer and have not had chemotherapy before.
- Your doctor plans to give you at least 4 cycles of doxorubicin.
- Your heart function (LVEF) is 55% or higher on an echocardiogram.
- You are not pregnant or breastfeeding.
- You are not currently taking blood thinners, certain pain relievers (like ibuprofen or ketorolac), or other heart-protective medications.
- You do not have a history of heart failure, angina, uncontrolled high blood pressure, or heart surgery in the last 3 months.
- Your kidney and liver function tests are within acceptable ranges.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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