Treatment
Pentoxifylline clinical trials
We’re tracking 16 recruiting studies that include Pentoxifylline, each written for real people, not researchers, below.
Recruiting studies
- NCT07085806Recruiting
Pentoxifylline for liver growth after donor surgery
This study tests if a medicine called pentoxifylline can help your liver grow faster after donating a large part of it. You would take the medicine before and after your donor surgery.
New DelhiAges 18–55 - NCT07086794RecruitingEarly Phase 1
Testing if pentoxifylline helps reduce cocaine use
This study tests whether a medication called pentoxifylline can reduce cocaine use in people who smoke or inject cocaine but aren't ready to stop. You'll receive either pentoxifylline or a placebo to see if it helps control cravings or use.
Lexington, KentuckyAges 18–55 - NCT05575505RecruitingPhase 2
Pentoxifylline added to ulcerative colitis treatment
This trial tests whether adding the medicine pentoxifylline to standard care can help people with ulcerative colitis. It’s designed to see if this combination improves symptoms by changing inflammation.
Al MansurahAges 18–75 - NCT05611268Recruiting
Pentoxifylline added for Eisenmenger syndrome
This study tests whether adding pentoxifylline to usual care can improve health outcomes in people with Eisenmenger syndrome. It may help reduce problems related to blood flow and vessel function, especially for those not recently hospitalized.
São PauloAges 10–80 - NCT05637086RecruitingPhase 2
Test pentoxifylline plus celecoxib for grand mal epilepsy on phenytoin
This Phase 2 study tests whether adding two medicines—pentoxifylline and celecoxib—to current phenytoin treatment is safe and may help people with grand mal (generalized) epilepsy. It focuses mainly on safety while you stay on a single epilepsy medicine.
Al MansurahAges 18–75 - NCT06634056RecruitingPhase 2
Preventing lung inflammation during chemoradiation for stage III lung cancer
This trial tests whether two medicines, pentoxifylline and vitamin E, can help prevent a type of lung inflammation called pneumonitis in people with stage III non-small cell lung cancer who are getting chemoradiation and a checkpoint inhibitor. These medicines are already used for other conditions and may lower the risk of this side effect.
Toronto, OntarioAges 18 years+ - NCT06998628RecruitingPhase 2
Pentoxifylline for rheumatoid arthritis inflammation
This study tests if pentoxifylline, a medicine typically used for circulation, can help reduce joint inflammation in people with rheumatoid arthritis who still have active symptoms despite taking standard DMARDs.
Damietta, Damietta GovernorateAges 18–70 - NCT07137793RecruitingPhase 2
Pentoxifylline to protect the heart during breast cancer chemo
This trial tests if a medicine called pentoxifylline can help prevent heart damage caused by doxorubicin, a common chemotherapy drug for breast cancer. If you are starting doxorubicin for the first time, this study may offer added heart protection.
DamanhūrAges 18–60 - NCT07252518Recruiting
Pentoxifylline and CoQ10 for Sperm Motility
This trial tests if adding pentoxifylline to CoQ10 (a natural supplement) works better than CoQ10 alone to improve sperm movement in men with low sperm motility. If you have been trying to conceive and your semen analysis shows low motility, this study may help.
Dhaka, ShahbagAges 20–50 - NCT07349472RecruitingPhase 2
Pentoxifylline for ulcerative colitis
This trial tests if the drug pentoxifylline can help people with mild to moderate ulcerative colitis. It may offer a new treatment option for those not on other strong medications.
Al FayyumAges 18–70 - NCT05795647RecruitingPhase 2
Testing pentoxifylline and vitamin E for jaw bone damage
This trial tests a combination of medicines (pentoxifylline and tocopherol, a form of vitamin E) to treat damage to the jaw bone caused by bone-strengthening drugs. If you have Stage 2 MRONJ and meet other criteria, this treatment may help heal the bone.
LimogesAges 18 years+ - NCT07499817RecruitingPhase 3
Effect of pentoxifylline on womb lining and frozen embryo transfer
This trial tests if a medication called pentoxifylline can help thicken the womb lining and improve success rates for frozen embryo transfers. It may be an option for people with a thin womb lining before their procedure.
Banī Suwayf, Beni Suweif GovernorateAges 18–43 - NCT06912763RecruitingPhase 2
Reversing radiation side effects in head and neck cancer
This trial tests a combined treatment (a statin and a drug that helps blood flow) to reverse long-term swelling and tissue hardening caused by head and neck radiation. It may help people who have had these side effects for more than 6 months.
Houston, TexasAges Any age - NCT04217733RecruitingPhase 3
Ethosuximide plus pentoxifylline for IBS belly pain
This Phase 3 study tests whether two medicines (ethosuximide and pentoxifylline) can reduce belly pain from irritable bowel syndrome (IBS). It may help people whose IBS pain has been moderate to severe recently and who can keep their current IBS treatment steady.
TantaAges 18 years+ - NCT06040489RecruitingPhase 2/Phase 3
Oral treatment for leishmaniasis in older adults
This trial tests if oral medicines can treat cutaneous (skin) or mucosal leishmaniasis in people aged 60 and older. It compares two different pills to find a safer, easier option for elderly patients.
Brasília, Federal DistrictAges 50 years+ - NCT06494111RecruitingPhase 2
Preventing neck swelling after radiation for throat cancer
This study tests two medicines—pravastatin (a statin) and a combination of pentoxifylline and Vitamin E—to see if they can prevent long-term swelling (lymphedema) and scarring in the neck after radiation therapy for throat cancer. Participants receive one of the medicines daily for 2 years, and regular scans help monitor any changes.
Houston, TexasAges 18 years+
What Pentoxifylline is being studied for
Conditions with recruiting Pentoxifylline studies.
Common questions
- Are there clinical trials studying Pentoxifylline?
- Yes. Clin2 currently lists 16 recruiting studies that include Pentoxifylline, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Pentoxifylline trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Pentoxifylline an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Pentoxifylline or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.