Study of why glioblastoma comes back

This study aims to improve understanding of glioblastoma (and gliosarcoma) by preserving live, usable brain-tissue samples during brain surgery. If you’re having repeat tumor surgery or your scans suggest these cancers, the study may ask to collect tissue for research.

This trial studies different treatment regimens for people with glioblastoma that is either newly diagnosed or has come back. It aims to find which treatment approach works best for controlling the tumor and improving outcomes.

This trial studies whether operating on a brain tumor that has returned can help people with recurrent glioblastoma. It focuses on people whose scans suggest surgery is safe for important speech and movement brain areas.

This trial compares surgery to the best non-surgical treatment for people whose glioblastoma has come back. The goal is to see which approach helps people live longer with a better quality of life.

This study uses MRI scans to learn more about the biology of glioblastoma before and after surgery. It may help doctors understand how the tumor behaves and improve future treatments.

This early study looks at a treatment plan (including resection/surgery and an added medicine) for glioblastoma that has come back after standard therapy. The goal is to see how well it controls tumor growth and whether it is tolerable.