Long-term study of saroglitazar for PBC with cirrhosis
Treatments studied
Part of Digestive system clinical trials.
This study tests a new drug called saroglitazar to see if it can improve long-term outcomes in people with primary biliary cholangitis (PBC) who have cirrhosis. It may be an option if you are already on UDCA or cannot take it, and if your liver function tests meet certain levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and have been diagnosed with primary biliary cholangitis (PBC).
- You are either on a stable dose of ursodeoxycholic acid (UDCA) for at least 6 months, or you cannot take UDCA and haven't taken it in the last 3 months.
- You have evidence of cirrhosis with specific blood test results (elevated ALP and bilirubin not too high).
- You do not have other liver diseases like hepatitis B or C, or severe liver complications (like being on a transplant list).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an experimental oral drug called seladelpar for people with PBC who also have cirrhosis that is well-controlled. The goal is to see if it helps improve liver health and manage symptoms without causing serious side effects.
This trial tests a new oral medication, saroglitazar magnesium, for people with Primary Biliary Cholangitis (PBC) who have not improved enough on standard therapy (UDCA) or cannot tolerate it. The goal is to see if it can help control liver enzymes and improve outcomes.
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This trial tracks how well the combination of ursodiol and seladelpar works in people with primary biliary cholangitis (PBC), a liver disease. It aims to see if this treatment helps control symptoms and liver function.
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