Clin2
NCT07234474Possibly a fitNot yet recruiting

Study of YK012 for primary membranous nephropathy

Primary Membranous Nephropathy

Treatments studied

Part of Kidney & urinary clinical trials.

This trial tests an experimental drug called YK012 for people with a serious type of kidney disease called primary membranous nephropathy. It aims to see if the drug is safe and helps when other treatments have stopped working.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
66 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 80 years old.
  • You were diagnosed with primary membranous nephropathy (a kidney condition) by a kidney biopsy within the last 10 years.
  • Your kidney disease is considered very high-risk and you have tried other treatments that did not work.
  • Your kidney function, measured by a blood test called eGFR, is at least 45.
  • You have not had certain treatments for this condition before.
  • You do not have other serious health problems like active infections, cancer within the last 5 years, or uncontrolled high blood pressure.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06982729Recruiting· Phase 1
Testing YK012 for primary membranous nephropathy

This trial tests a new drug called YK012 for people with primary membranous nephropathy, a kidney disease where protein leaks into the urine. The goal is to see if this treatment can reduce protein loss and protect kidney function.

Beijing, Beijing Municipality
NCT06893328Recruiting
Real-world study of primary membranous nephropathy

This study looks at how well a treatment works for people with primary membranous nephropathy (PMN), a kidney condition. It is meant for patients who still have high protein in their urine despite taking standard blood pressure medicines.

Guangzhou, Guangdong
NCT06470191Recruiting· Phase 2/Phase 3
B007 for primary membranous nephropathy

This trial tests a new drug called B007 for people with primary membranous nephropathy, a kidney condition. It aims to see if B007 can help reduce protein in the urine and protect kidney function.

Beijing
NCT05668403Recruiting· Phase 1
Subcutaneous anti-CD20 antibody for primary membranous nephropathy

This Phase 1 study tests a skin-under-the-bone (subcutaneous) antibody medicine that targets CD20 on certain immune cells. It aims to see safety and how the drug may work in people with primary membranous nephropathy, a kidney disease that can cause high urine protein.

Zhengzhou, He'nan
NCT07765537Not yet recruiting· Phase 1/Phase 2
Study of FKC289 for membranous nephropathy that has come back

This study tests a new treatment called FKC289 for people with membranous nephropathy (a kidney disease) that has not improved or has returned after other treatments. It aims to see if the treatment is safe and helps reduce protein in the urine.

Hefei, Anhui
NCT07289763Recruiting· Phase 2
Study of SHR-2173 for primary membranous nephropathy

This trial tests an investigational drug called SHR-2173 for people with primary membranous nephropathy, a kidney disease that causes protein leakage. The study aims to see if the drug is safe and effective, and it involves periodic injections and monitoring.

Nanjing, Jiangsu

Hear when a new Primary Membranous Nephropathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.