Radiation seeds with immunotherapy for advanced solid tumors
Part of Cancer clinical trials.
This study combines tiny radioactive seeds placed directly into tumors with an immunotherapy drug that helps the immune system fight cancer. It is for patients with advanced or returning tumors that have not responded well to other treatments, and aims to see if this combination can shrink tumors and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have been diagnosed with a solid tumor that is primary, has come back, or has spread.
- You have at least one tumor that can be measured on a scan.
- Your doctor thinks it is safe to insert the radioactive seeds into the tumor using a needle guided by CT or PET imaging.
- You are planning to receive or are eligible for an immunotherapy drug (a checkpoint inhibitor).
- You are in reasonably good health (able to care for yourself, no serious heart or lung problems) and have adequate organ function (blood counts, liver and kidney tests within limits).
- You have not had prior radiation seed therapy at the same site, and you do not have an active infection, autoimmune disease, or bleeding disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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