Lubiprostone for slow-transit constipation in adults
Treatments studied
Part of Digestive system clinical trials.
This study tests whether lubiprostone (Amitiza) can help people with slow-transit constipation. If you have few bowel movements and tests show that stool moves slowly through your colon, this treatment may help you go more regularly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with chronic functional constipation (Rome IV criteria).
- You have fewer than 3 spontaneous bowel movements per week.
- A colon transit study showed that stool moves slowly through your colon.
- You are at least 18 years old and can use effective birth control if needed.
- You have not taken lubiprostone before and do not have certain other health conditions (like severe depression, thyroid disease, or inflammatory bowel disease).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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