Clin2
NCT07304271Possibly a fitRecruiting

Paclitaxel in the belly plus chemo vs chemo alone for stomach cancer spread

Gastric Cancer Peritoneal Metastases

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests whether adding chemotherapy directly into the abdomen (intraperitoneal paclitaxel) to standard intravenous chemotherapy improves outcomes for people with stomach or esophageal cancer that has spread to the lining of the abdomen (peritoneal metastasis).

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
262 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have stomach or lower esophageal cancer confirmed by biopsy
  • Cancer has spread to the lining of your abdomen (confirmed by biopsy or fluid sample)
  • You have had a laparoscopy (small camera surgery) to check the extent of spread within the last 4 weeks
  • You are well enough to carry out daily activities (ECOG 0-1)
  • You are at least 18 years old and expected to live at least 3 more months

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07304258Not yet recruiting· Phase 2
Combination therapy for stomach cancer spread to the abdomen

This trial tests a combination of treatments for stomach cancer that has spread to the lining of the abdomen. The goal is to see if this approach can shrink or control the cancer, potentially making surgery possible.

Shijiazhuang, Hebei
NCT07855640Recruiting
Immunotherapy plus chemo for advanced stomach cancer with fluid in belly

This trial tests a new combination for advanced stomach cancer that has spread and caused fluid buildup in the belly (malignant ascites). It combines an immunotherapy drug (anti-PD-1) with standard chemotherapy and a targeted chemotherapy given directly into the belly to see if it can shrink the cancer and help you feel better.

Hangzhou, Zhejiang
NCT07001748Recruiting· Phase 2/Phase 3
Testing abdominal chemo plus standard chemo for stomach cancer spread

This trial tests adding the chemotherapy drug paclitaxel directly into the abdomen (intraperitoneal) along with standard IV chemotherapy for people with stomach or gastroesophageal junction cancer that has spread to the lining of the abdomen. The goal is to see if this combination helps control the cancer better than standard treatment alone.

Irvine, California
NCT05977998Recruiting· Phase 2
Paclitaxel given during surgery for stomach cancer spread to the belly

This trial studies whether adding paclitaxel chemotherapy around the time of surgery can improve outcomes for people with stomach or gastroesophageal junction adenocarcinoma that has spread to the lining of the abdomen (peritoneum). It targets cancers confirmed by testing of belly fluid or by laparoscopy/laparotomy, and may help by treating cancer cells right at the time of surgery.

Houston, Texas
NCT07795749Recruiting· Phase 2
Intraperitoneal paclitaxel with systemic therapy for gastrointestinal cancer with peritoneal spread

This study tests a treatment that combines chemotherapy given directly into the abdomen (intraperitoneal) with standard systemic chemotherapy for people whose gastrointestinal cancer has spread to the lining of the abdomen (peritoneal carcinomatosis). It aims to control the cancer and improve how patients feel.

Orange, California
NCT06675136Recruiting· Phase 1
Nab-paclitaxel PIPAC with paclitaxel and ramucirumab for stomach cancer spread to belly lining

This trial tests a new way to deliver chemotherapy directly into the belly for stomach cancer that has spread to the lining of the abdomen (peritoneal metastases). It also combines two standard chemotherapy drugs. The goal is to see if this approach can help people whose cancer progressed after first treatment.

Duarte, California

Hear when a new Gastric Cancer Peritoneal Metastases trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.