Comparing infection monitoring vs. antibiotic prevention in stem cell transplant
Treatments studied
Part of Infections clinical trials.
This trial compares two ways to prevent infections after a stem cell transplant: using a standard antibiotic (ceftriaxone) or closely watching for germs in the blood and treating only if needed. It aims to find which method is safer and more effective for people receiving a stem cell transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are receiving your own or a donor's stem cells from blood, bone marrow, or cord blood.
- You are 18 years old or older.
- You must be able to understand and sign a consent form.
- You have not had an active infection for at least 2 weeks before the transplant.
- You do not have a current fungal infection or fever without a known cause.
- You are not taking antibiotics now (except cotrimoxazole).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial follows people who have had a recent organ or stem cell transplant to learn more about infections and how they can be prevented. You may be asked to provide samples and information over time.
This Phase 2 study tests an oral “fecal microbiotherapy” treatment given before and around an allogeneic (donor) stem-cell transplant to help prevent transplant-related complications. It may help by improving gut and immune function during the high-risk transplant period.
This study will track how certain hard-to-treat bacteria spread and cause infections in people who are in the intensive care unit (ICU) or have had a stem cell transplant. The goal is to better understand and prevent these infections in vulnerable patients.
This trial tests whether a special herbal treatment applied to the skin can help prevent infections around the bottom that are caused by diarrhea after a stem cell transplant. It may be an option for people who are getting a transplant for the first time.
This trial tests a special type of donor immune cell (depleted of CD45RA cells) to see if it can prevent serious viral infections in people at high risk after a stem cell transplant from a half-matched donor.
This study is for people who have had a stem cell or solid organ transplant. It aims to predict who might get a serious infection and help doctors manage their care better.
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