Study of Tenapanor for Chronic Constipation in Adults
Treatments studied
Part of Digestive system clinical trials.
This study tests an investigational drug called tenapanor for people with chronic idiopathic constipation (constipation with no clear cause). It aims to see if the drug can safely improve bowel movements in adults.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have chronic constipation (not caused by another condition like IBS).
- You are willing to use birth control if needed, or are not able to have children.
- You have daily access to a smartphone, tablet, or computer to fill out a diary.
- You have not had recent stomach or bowel surgery, or a history of certain medical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial checks the safety of tenapanor in children and teens (ages 6 to under 18) with IBS-C. It is only for people who finished a previous related study and agreed to continue follow-up.
This study tests whether a medication called tenapanor can help relieve constipation in people with Parkinson's disease. If you have Parkinson's and have been struggling with constipation for at least 6 months, this trial may offer a new option to improve bowel regularity.
This trial tests a new medicine called IN-114199 in healthy people to see if it is safe and how the body handles it. It is a first-in-human study, meaning it is the first time this drug is given to people.
This study tests whether adding a medication called tenapanor (which helps reduce phosphorus absorption in the gut) to your current phosphate binder can improve blood phosphorus levels in people on hemodialysis. It aims to find a safe and effective way to lower phosphorus, which is important for bone and heart health.
This trial tests a new medicine called CMTS4520 to help adults with chronic constipation have more regular bowel movements. It aims to see if the medicine is safe and effective for people who have hard, infrequent stools.
This study tests a new medicine called plecanatide for children and teens with functional constipation. It aims to see if it helps improve bowel movements compared to a placebo (a pill with no medicine).
Hear when a new Chronic Idiopathic Constipation (CIC) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.