Testing cemiplimab before surgery for Merkel cell carcinoma
Treatments studied
Part of Cancer, Infections, Skin clinical trials.
This trial tests whether giving the immunotherapy drug cemiplimab before surgery can improve outcomes for people with stage I or II Merkel cell carcinoma. If you qualify, you would receive cemiplimab before your sentinel lymph node biopsy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Merkel cell carcinoma at stage II, or stage I with a tumor at least 1 cm (about 0.4 inches) across.
- You are 18 years or older.
- Your primary tumor has already been removed, but you still need a sentinel lymph node biopsy.
- Your overall health is good (ECOG performance status 0-2).
- You have adequate organ function (kidneys, liver, blood counts).
- If you can become pregnant, you must agree to use highly effective birth control during treatment and for 6 months after the last dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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