Microneedling with chemo cream vs steroid cream for limited vitiligo
Part of Skin clinical trials.
This study tests whether microneedling (tiny needles that prick the skin) combined with a chemotherapy cream (5-fluorouracil) works better than a strong steroid cream for treating vitiligo patches on a small area of the body. It's for people with limited vitiligo (covering no more than 10% of their body) who have not used other vitiligo treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are willing to join the study and follow the rules.
- You are between 5 and 70 years old.
- Your vitiligo covers 10% or less of your body.
- You haven't used any other vitiligo treatments (like creams, light therapy, or pills).
- You are not pregnant or breastfeeding.
- You don't have conditions like anemia, bleeding problems, epilepsy, or a history of keloids (thick scars).
- You are not allergic to 5-fluorouracil or strong steroids.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a new combination treatment (microneedling plus a non-steroidal ointment called crisaborole) can help repigment patches of vitiligo that have been stable for a while. It is for people with non-segmental vitiligo that is not spreading.
This trial tests whether taking small doses of steroids by mouth for a few days before and after a skin cell transplant (NCES) can reduce the white halo that sometimes forms around the treated area. It is for people with stable vitiligo on the face or trunk that hasn't responded to creams or light therapy.
This study tests whether applying a strong steroid cream (betamethasone) with the help of ultrasound waves (phonophoresis) can repigment vitiligo patches. It aims to see if this combination works better than the cream alone.
This trial compares two types of needle treatments (needling and microneedling) combined with light therapy to see which works better for people with vitiligo that has lasted more than a year.
This trial tests whether adding short bursts of steroid pills to a skin cell transplant procedure can improve results for people with stable vitiligo on hard-to-treat areas like elbows and knees.
This trial tests whether combining narrowband UVB light with topical steroids can help treat vitiligo, and looks at specific blood markers (CXCL11 and TEMRA) to see how the treatment affects the immune system. It may help patients with stable, non-segmental vitiligo who have not used systemic therapy in the last 3 months.
Hear when a new Vitiligo trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.