Clin2
NCT07416123Worth exploringRecruiting

Study of a new drug for advanced solid tumors

Solid TumorsUrothelial Carcinoma

Part of Cancer clinical trials.

This trial tests an experimental drug, GEN1106, for people with solid tumors that have not responded to standard treatments. It aims to see if the drug can help shrink or control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
103 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Your cancer must have progressed or not responded to all standard treatments (including chemo, immunotherapy, or targeted therapy).
  • You need to have at least one measurable tumor, meaning it can be seen on scans and measured.
  • You should be able to care for yourself and be up and about (a performance status of 0 or 1).
  • For the first part of the study, any solid tumor type is allowed. For later parts, you must have metastatic bladder cancer.
  • You cannot have received a type of drug called a topoisomerase 1 inhibitor-based antibody-drug conjugate before.
  • You need to be at least 4 weeks past any previous cancer treatment or 5 drug half-lives, whichever is shorter.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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