Fecal transplant for primary sclerosing cholangitis
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether a fecal microbiota transplant (a procedure that puts healthy bacteria from a donor's stool into your gut) can help people with primary sclerosing cholangitis (PSC), a liver disease. It aims to see if this treatment can slow the disease and improve liver health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with primary sclerosing cholangitis (PSC) affecting the large bile ducts.
- You also have inflammatory bowel disease (IBD), like ulcerative colitis or Crohn's disease, that has been quiet (no flare-ups) for at least 6 months.
- Your liver tests show certain abnormalities (like elevated alkaline phosphatase or bilirubin levels).
- You have been taking a stable dose of ursodeoxycholic acid (UDCA) for at least 6 months.
- You are willing to use effective birth control if you are a woman who can become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new treatment called LB-P8 for people with primary sclerosing cholangitis (PSC), a liver disease. It aims to see if LB-P8 is safe and can help slow the disease down. You may join if you meet certain health requirements.
This trial tests whether a fecal microbiota transplantation (FMT), which transfers healthy bacteria from a donor into your gut, can reduce severe irritable bowel syndrome (IBS) symptoms. FMT is being studied as a possible new treatment for people with IBS that hasn't improved with other treatments.
This trial tests whether a fecal (stool) transplant from a healthy donor can help people with both PSC and inflammatory bowel disease. It aims to see if the treatment can improve liver health and reduce inflammation. You must have early to moderate liver scarring and be on stable medications.
This study tests whether stool from healthy donors can help people with advanced liver disease (cirrhosis) who have had complications like fluid buildup. You would receive the transplant through a colonoscopy or enema.
This trial studies whether transferring healthy gut bacteria (from a donor sample) can improve outcomes for people with liver cirrhosis who have worsening complications. It may help by changing the gut microbiome, which can influence inflammation and liver health.
This trial tests whether transplanting healthy gut bacteria (from donor stool) can improve outcomes in people with cirrhosis. If you have mild to moderate cirrhosis, you may be able to join.
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