Topical Metformin Cream for Mild Psoriasis
Treatments studied
Part of Hormones & metabolism, Skin clinical trials.
This trial tests whether a cream containing metformin (a diabetes medication) can help reduce mild psoriasis patches on the skin. Researchers want to see if applying it directly to affected areas improves symptoms without needing pills or injections.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Diagnosed with mild plaque psoriasis (the most common type) affecting less than 10% of your body
- Have not taken systemic psoriasis medications (pills or injections) in the past 3 months, except retinoids
- Have not used topical psoriasis treatments (creams or ointments) in the past 2 weeks
- Not currently taking metformin pills, antimalarial drugs, blood pressure medications (ACE inhibitors, calcium channel blockers, beta blockers), or NSAIDs like ibuprofen in the past 2 weeks
- No psoriatic arthritis (joint pain from psoriasis) and not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a cream called diacerein for mild plaque psoriasis. If you have small patches of psoriasis and haven't used other treatments recently, this cream might help reduce redness and scaling.
This study tests a cream made from a natural plant compound (coumarin) to see if it can help treat plaque psoriasis. If you have mild-to-moderate psoriasis and haven't used certain other treatments recently, this trial may be an option for you.
This study tests an herbal cream made from Ciplukan (a plant) on plaque psoriasis. If you are an adult with mild-to-moderate psoriasis and are not already using other treatments, this trial may help find a gentler option.
This trial tests whether a painless electrical current (iontophoresis) can deliver metformin through the skin to reduce knee osteoarthritis pain in postmenopausal women. If you have moderate knee arthritis and are not taking diabetes medications, you may be able to join.
This trial tests a microneedling technique combined with three topical medications (metformin, tranexamic acid, and a modified Kligman's formula) to treat melasma, a common skin condition causing dark patches. The goal is to see if this approach safely and effectively reduces melasma in eligible women.
This trial tests a new topical cream for people with mild or moderate plaque psoriasis. It aims to see if the cream can improve psoriasis patches on the skin.
Hear when a new Psoriasis Vulgaris trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.