Camlipixant for abdominal symptoms in IBS-D and IBS-M
Part of Digestive system clinical trials.
This study tests whether a new drug called camlipixant can reduce belly pain and other uncomfortable symptoms in people with irritable bowel syndrome that causes diarrhea or mixed symptoms. The trial compares camlipixant to a placebo (inactive pill) to see if it works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–80 years old
- You have been diagnosed with IBS-D (diarrhea-dominant) or IBS-M (mixed type) using Rome IV criteria
- Your IBS symptoms are moderate or severe, not mild
- You have ongoing abdominal discomfort (weekly pain score of 4 or higher) plus frequent loose or hard stools during a run-in period
- You have not had successful treatment with more than two different classes of IBS medications
- You do not have inflammatory bowel disease, celiac disease, or a recent infection of the gut
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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