Freezing treatment with or without medication for keloid scars
Part of Skin clinical trials.
This study compares freezing treatments (cryosurgery) alone versus combining freezing with two injectable medications (5-FU and triamcinolone) to treat keloids — raised, thick scars that can be painful or itchy. The goal is to see which approach works better for flattening and improving the scar.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a keloid (a raised, thick scar) that is between 1 and 10 cm across — about the size of a pea to a small apple.
- The keloid must have been present for at least one year.
- If you are a woman, you cannot be pregnant, planning to become pregnant, or breastfeeding.
- You cannot have had any prior treatment for this same keloid in the last 12 months.
- You must not have active infection, inflammation, or an open sore on or near the keloid, and no chronic kidney or liver disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests if ritlecitinib, an oral medication, can treat existing keloids (raised scars that grow beyond the original wound) or prevent new ones from forming after surgical removal. It may help people with large or painful keloids that haven't responded to other treatments.
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