Testing trigger methods for poor egg response in IVF
Part of Women’s health & pregnancy clinical trials.
This trial compares two methods to trigger final egg maturation in people undergoing IVF who have had poor response to fertility medications in past cycles. The goal is to improve egg quality and increase chances of successful pregnancy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are classified as a POSEIDON group 3 or 4 poor responder (meaning you produced few eggs or poor-quality eggs in previous IVF attempts)
- Your current IVF cycle uses GnRH antagonist medications (a type of hormone blocker used in some IVF protocols)
- You do not have hypogonadotrophic hypogonadism (a condition where the pituitary gland doesn't produce enough hormones to trigger natural reproduction)
- You do not have endometriosis (a condition where tissue similar to the uterine lining grows outside the uterus)
- You do not have a history of recurrent miscarriages (three or more consecutive pregnancy losses)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether using multiple smaller doses of a trigger medication works better than one large dose for women who respond very strongly to fertility drugs during IVF. The goal is to improve egg quality and reduce side effects in women whose ovaries produce many eggs.
This trial compares dydrogesterone with a GnRH antagonist to see which works better for women with a low number of eggs (poor responders) who are undergoing two rounds of egg retrieval in one cycle. It may help improve outcomes for those with specific fertility challenges.
This trial tests whether doing two shorter rounds of hormone stimulation in one menstrual cycle (dual ovarian stimulation) leads to more live births than the usual two separate stimulation cycles for women who have a low egg reserve. The goal is to find a better way to help women who have had limited success with IVF.
This study compares two ways to prepare the ovaries for egg retrieval before IVF: using a progestin hormone or a GnRH antagonist. The goal is to see which method leads to more successful embryo transfers.
This study compares two methods of stimulating the ovaries before IVF: one using a standard hormone (hCG) and another using a different protocol. The goal is to see if the new method works as well as the standard one, while possibly being more cost-effective.
This trial tests how well a hormone treatment (hMG) works for people doing IVF with genetic screening of embryos. It may help if you have normal ovarian reserve and are not using donor sperm.
Hear when a new Infertility trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.