Clin2
NCT07602322Possibly a fitNot yet recruiting

Precision combination therapy after car-t for b-cell lymphoma

Large B-cell Lymphoma

Part of Cancer clinical trials.

This study tests a new combination of medicines, chosen based on your tumor's specific features, for people whose lymphoma did not respond to CD19 CAR-T therapy. The goal is to find a more effective treatment option for this difficult situation.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
60 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have a type of large B-cell lymphoma (a blood cancer), such as diffuse large B-cell lymphoma or high-grade B-cell lymphoma
  • You have already received CD19 CAR-T cell therapy, and your lymphoma did not shrink or it came back after that treatment
  • You can provide a tumor tissue sample (new or old) that tests positive for a protein called CD20
  • You are generally able to care for yourself (ECOG score 0, 1, or 2) and have adequate organ function

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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