Immune test for cervical lesions in HPV16/18-positive women
Part of Cancer, Women’s health & pregnancy clinical trials.
This study uses a simple blood test to see if it can help detect cervical lesions in women infected with HPV types 16 or 18. The goal is to find a less invasive way to identify who might need further checks, like a colposcopy or biopsy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had a cervical cytology (Pap smear) result.
- You are willing to undergo a colposcopy and a cervical biopsy if needed.
- You have not already been diagnosed with CIN2 or worse (moderate to severe cervical changes).
- You have not had previous cervical treatments like ablation, conization, chemotherapy, radiation, or immunotherapy.
- You do not have other cancers that have not been in remission for the last 2 years, serious immune diseases, or active infections.
- You are not pregnant or breastfeeding, and you can follow up with the study team.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing a new, low-cost, lab-free screening test for cervical cancer. The goal is to see if it can detect early signs of cancer without needing a doctor's visit or a lab — making it easier for women to get screened.
This trial compares a liquid-based cytology test with a molecular screening test to find early changes in the cervix that could lead to cancer. It may help you understand which test is better at detecting these changes before they become serious.
This study checks whether “liquid biopsies” (blood tests that look for cancer-related signals) can help monitor how HPV-related cancers respond to treatment. It may help doctors spot changes earlier during care.
This early (Phase 1) study tests a new treatment for people with long-lasting mild abnormal Pap test results (ASC-US or LSIL) who also have HPV16 found on testing. It aims to find out whether the treatment can be given safely and may affect the HPV and abnormal cell changes.
This study tests if a self-collected sample for HPV testing works as well as standard colposcopy to prevent cervical cancer. If you've recently had an abnormal cervical cancer screening and need a colposcopy, this trial may be an option for you.
This trial checks how well cervical cancer responds to surgery, radiation, and chemotherapy by measuring HPV DNA and RNA in blood and cervical mucus. It aims to improve monitoring during treatment.
Hear when a new CIN 2/3 trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.