Low-dose vs standard-dose isotretinoin for moderate to severe acne
Treatments studied
Part of Skin clinical trials.
This study compares two different dosages of isotretinoin (a powerful acne medication) to see which works better and causes fewer side effects. Isotretinoin is typically used for acne that hasn't improved with other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 45 years old
- You have moderate to severe acne vulgaris (a dermatologist has confirmed this)
- You are not pregnant, trying to become pregnant, or breastfeeding
- You have not taken any acne treatments in the past (including creams, oral medications, or antibiotics)
- You do not have a history of hormone-related conditions like PCOS, high cholesterol, kidney disease, or liver disease
- You are not allergic to isotretinoin and are not currently taking corticosteroids
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether taking oral probiotics (live beneficial bacteria) can help reduce acne breakouts and inflammation in teenagers and young adults. Researchers want to see if probiotics work better than a placebo (inactive pill) for moderate acne.
This trial tests a weekly dose of isotretinoin (a strong acne medicine) versus a standard tetracycline antibiotic for treating moderate acne. It aims to find a simpler, effective option with fewer side effects.
This trial compares oral isotretinoin (a strong acne medication) to standard treatments for people with moderate acne and darker skin tones. It aims to find which treatment works best for skin of color.
This trial tests a treatment for dry eyes caused by isotretinoin, a drug used for severe acne. It aims to help people with moderate to severe acne who are already taking isotretinoin and experiencing dry eye symptoms.
This trial measures a blood protein called catestatin in people with moderate to severe acne. It aims to understand how catestatin relates to acne, which may help guide future treatments.
This study looks at the link between acne and cholesterol levels in young adults. It enrolls healthy volunteers who have never had acne and aren't taking any medications to see if there is a connection.
Hear when a new Acne Vulgaris trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.