Clin2
NCT07677293Possibly a fitNot yet recruiting

New drug plus chemotherapy for advanced stomach cancer with liver spread

Gastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma

Treatments studied

Part of Cancer, Digestive system clinical trials.

This study tests a new drug (Retlirafusp alfa) combined with chemotherapy against a standard immunotherapy drug with chemotherapy for people with advanced stomach cancer that has spread to the liver. It aims to see if the new combination works better as a first-line treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
332 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • You must have advanced stomach or lower esophagus cancer that has spread to your liver.
  • You must not have had any prior treatment for advanced cancer (except if you finished adjuvant/neoadjuvant therapy more than 6 months before recurrence).
  • You must be in good physical condition (able to take care of yourself and be up and about).
  • You must not have serious autoimmune diseases or have received certain immunotherapies before.
  • You must agree to use effective birth control during the study and for 120 days after the last dose.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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