Clin2
NCT07680569Possibly a fitNot yet recruiting

Study of HCB101 combined with other drugs for advanced stomach or gastro-esophageal cancer

GC/GEJC

Treatments studied

Part of Cancer, Digestive system clinical trials.

This study tests a new combination treatment for advanced stomach or gastro-esophageal cancer that has not responded to standard treatments. The trial aims to see if the drug combination is safe and effective, potentially offering a new option for people with this type of cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be at least 18 years old.
  • You must have advanced stomach or gastro-esophageal cancer that is HER2-negative and CLDN18.2-positive (a specific protein marker).
  • You must have at least one measurable tumor that can be evaluated.
  • You must not have had prior systemic cancer therapy (including immunotherapy) for this cancer.
  • You must have adequate organ function and be in generally good health (ECOG performance status 0–1).
  • You must not have active brain metastases, uncontrolled heart problems, or certain infections like HIV, hepatitis B/C, or tuberculosis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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