Etanercept for improved live birth in low ovarian reserve IVF patients
Part of Women’s health & pregnancy clinical trials.
This study tests whether etanercept, a drug that reduces inflammation, can improve the chances of having a baby in women with low ovarian reserve who are undergoing IVF. It may help by calming the immune system to create a better environment for embryo implantation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 42 years old.
- You have been diagnosed with diminished ovarian reserve (DOR), meaning at least two of the following: AMH level 1.1 ng/mL or lower, fewer than 7 antral follicles on ultrasound, or FSH levels between 10 and 25 U/L on days 2–4 of your cycle twice in a row.
- Your male partner has had a normal semen analysis (with specific counts and motility).
- You plan to undergo in vitro fertilization (IVF) with embryo transfer.
- You have not had ovarian surgery, have no uterine abnormalities affecting implantation, and have no untreated uterine conditions like adhesions or endometritis.
- You have not had more than two failed embryo transfers, no history of cancer with chemo/radiotherapy, and no autoimmune diseases like lupus or rheumatoid arthritis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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